WebMore recently, SLC11A1 has been reported to be expressed in innate lymphocytes and enhance their activation [25]. The role of SLC11A1 extends beyond its well-established function as a host resistance gene. Recent studies have implicated it in both inflammatory and autoimmune disorders. Meta analysis identified the SLC11A1 locus as play- WebNov 22, 2024 · lacking SLC11A1 when we restricted Salmonella access to magnesium by impairing its uptake. Together, these findings identify deprivation of the main group metal magnesium as the main resistance mechanism of SLC11A1 against Salmonella. S olutecarrierfamily11,member1[SLC11A1;also called natural resi stance-associated …
Age- and gender-dependent association of SLC11A1 …
WebSLC11A1, located on the human chromosome 2q35, is an important regulator of macrophage responses to MTB (McHenry et al., 2024). Genetic variants of SLC11A1 have … WebThe polymorphism of the SLC11A1 gene (rs3731865) was associated with visceral leishmaniasis-HIV coinfection, suggesting a possible genetic mechanism involved in the … low prices vacation packages to europe 2016
Slc11a1 Enhances the Autoimmune Diabetogenic T-Cell Response …
WebSLC11A1 (formerly Human natural resistance–associated macrophage protein 1 (NRAMP1)) has been associated with susceptibility to tuberculosis. 94 The importance of … WebNov 22, 2024 · The pleiotropic host resistance factor SLC11A1 (NRAMP1) defends against diverse intracellular pathogens in mammals by yet-unknown mechanisms. We compared Salmonella infection of coisogenic mice with different SLC11A1 alleles. WebSlc11a1 (formerly Nramp1) is a proton/divalent cation transporter that regulates cation homeostasis in macrophages. Slc11a2 mediates divalent cation uptake via the gut and delivery into cells. The mode of action of the two transporters remains controversial. Heterologous expression in frog oocytes shows Slc11a2 is a symporter, whereas Slc11a1 … low price synthetic oil change