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Web10 jan. 2024 · The A1 helix is in the N-terminal of the core region and functions in interaction with NF-YB and NF-YC. The A2 is in the C-terminal and functions in specific recognition of the CCAAT element. The Histone Fold Domain (HFD) domain of the NF-YB and NF-YC proteins contains the DNA-binding domain and protein-protein interaction … Web26 jun. 2012 · The primary hormone-binding surface of the insulin receptor spans one face of the N-terminal β-helix of the α-subunit (the L1 domain) and an α-helix in its C-terminal segment (αCT). Crystallographic analysis of the free ectodomain has defined a contiguous dimer-related motif in which the αCT α-helix packs against L1 β-strands 2 and 3. mikes famous harley ct
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